Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 11/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373370 | 1.00 | SLC9A3 (0.42) | SLC9A3SLC6A2SLC6A4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7374165 | 0.99 | SLC9A3 (0.41) | SLC9A3SLC6A2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL7372071 | 0.91 | SLC9A3 (0.44) | SLC9A3ALDH1A1ELANELTA4H | |
| Hydrochloric Acid SCHEMBL7372662 | 0.90 | SLC9A3 (0.43) | SLC9A3ALDH1A1ELANELTA4H | |
| SCHEMBL7374090 | 0.85 | SLC6A2 (0.41) | SLC9A3SLC6A2SLC6A4TRPC6 | |
| SCHEMBL7372425 | 0.85 | SLC6A2 (0.41) | SLC9A3SLC6A2SLC6A4TRPC6 | |
| SCHEMBL7374729 | 0.82 | SLC6A2 (0.42) | SLC9A3SLC6A2SLC6A4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7370908 | 0.81 | SLC6A2 (0.42) | SLC9A3SLC6A2SLC6A4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7370910 | 0.81 | SLC6A2 (0.42) | SLC9A3SLC6A2SLC6A4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7376533 | 0.74 | SLC6A2 (0.60) | SLC9A3SLC6A2SLC6A4TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773463-A | DECALCIFICATION OF BRAIN DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-06-30 | — | — | US | disclosed |