Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC9A3 | P48764 | 8/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 7/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374090 | 1.00 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC9A3HTR1ASLC6A3 | |
| SCHEMBL7373370 | 0.85 | SLC9A3 (0.42) | SLC6A2SLC6A4SLC9A3TRPC6 | |
| SCHEMBL8638290 | 0.85 | SLC9A3 (0.42) | SLC6A2SLC6A4SLC9A3TRPC6 | |
| Hydrochloric Acid SCHEMBL7374165 | 0.84 | SLC9A3 (0.41) | SLC6A2SLC6A4SLC9A3TRPC6KDM1A | |
| SCHEMBL7375364 | 0.80 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC9A3HTR1ASLC6A3 | |
| Hydrochloric Acid SCHEMBL7376533 | 0.79 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC9A3TRPC6KDM1A | |
| Hydrochloric Acid SCHEMBL7368016 | 0.79 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC9A3HTR1ASLC6A3 | |
| SCHEMBL7334192 | 0.77 | KDM1A (0.38) | SLC6A2SLC6A4HTR1ASLC6A3KDM1A | |
| SCHEMBL7337058 | 0.77 | KDM1A (0.38) | SLC6A2SLC6A4HTR1ASLC6A3KDM1A | |
| SCHEMBL8653729 | 0.77 | KDM1A (0.38) | SLC6A2SLC6A4HTR1ASLC6A3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711272-A1 | INDANE AND TETRAHYDRONAPHTHALENE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | claimed |
| WO-1995004028-A1 | INDANE AND TETRAHYDRONAPHTHALENE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | claimed |
| US-5773463-A | DECALCIFICATION OF BRAIN DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-06-30 | — | — | US | disclosed |
| EP-0711272-A1 | INDANE AND TETRAHYDRONAPHTHALENE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004028-A1 | INDANE AND TETRAHYDRONAPHTHALENE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | disclosed |