Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851027 | 0.95 | TDP1 (0.70) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL8654324 | 0.93 | TDP1 (0.68) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL825596 | 0.89 | TDP1 (0.78) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL9814242 | 0.89 | TDP1 (0.84) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL3161153 | 0.89 | TDP1 (0.84) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL30294105 | 0.89 | TDP1 (0.84) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| Hydrochloric Acid SCHEMBL5864330 | 0.87 | TDP1 (0.75) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| Hydrochloric Acid SCHEMBL31547778 | 0.87 | TDP1 (0.75) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL2331250 | 0.87 | TDP1 (0.81) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL352046 | 0.87 | TDP1 (0.81) | TDP1SMN1; SMN2LMNATSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12162863-B2 | Modulators of stimulator of interferon genes (STING) | Ryvu Therapeutics S.A. (PL) | 2024-12-10 | — | — | US | disclosed |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2022-12-22 | — | — | US | disclosed |
| CN-112004845-B | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device | 三菱瓦斯化学株式会社 | 2022-05-31 | — | — | CN | disclosed |
| EP-3807264-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2021-04-21 | — | — | EP | disclosed |
| CN-112004845-A | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer, and semiconductor device | 三菱瓦斯化学株式会社 | 2020-11-27 | — | — | CN | disclosed |
| WO-2019238786-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2019-12-19 | — | — | WO | disclosed |
| EP-2585498-B1 | QUATERNIZED COPOLYMER | BASF SE (DE) | 2018-05-30 | — | — | EP | disclosed |
| EP-2082041-B1 | NOVEL GENES RELATED TO GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2018-03-14 | — | — | EP | disclosed |
| US-8911516-B2 | Quaternized copolymer | BASF SE (DE) | 2014-12-16 | — | — | US | disclosed |
| US-8809010-B2 | Method for prophylactic treatment of alzheimer's disease using inhibitors of glutaminyl cyclase and glutamate cyclases | PROBIODRUG AG (DE) | 2014-08-19 | — | — | US | disclosed |
| EP-0787711-A2 | Process for the preparation of alpha,beta-unsaturated carboxylic acids | F. HOFFMANN-LA ROCHE AG (CH) | 1997-08-06 | — | — | EP | disclosed |
| EP-0730578-A1 | INDOLYL GROUP CONTAINING COMPOUNDS AND THE USE THEREOF TO PROMOTE THE RELEASE OF GROWTH HORMONE(S) | MERCK & CO. INC. (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014666-A1 | INDOLYL GROUP CONTAINING COMPOUNDS AND THE USE THEREOF TO PROMOTE THE RELEASE OF GROWTH HORMONE(S) | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| EP-0230035-B1 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID CO (US) | 1994-10-12 | — | — | EP | disclosed |
| US-4728663-A | HYPOTENSIVE, ANTIARRHYTHMIA | AMERICAN CYANAMID COMPANY (US) | 1988-03-01 | — | — | US | disclosed |
| EP-0230035-A2 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |
| US-4434174-A | Treating cardiovascular diseases with N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines | BERLEX LABORATORIES, INC. (US) | 1984-02-28 | — | — | US | disclosed |
| US-4363808-A | N-(3-Phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines | BERLEX LABORATORIES, INC. (US) | 1982-12-14 | — | — | US | disclosed |
| EP-0034116-A2 | N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines | BERLEX LABORATORIES, INC. (US) | 1981-08-19 | — | — | EP | disclosed |
| US-4264494-A | Chromium complex dyestuffs for natural polyamides and synthetic nylons | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12162863-B2 | Modulators of stimulator of interferon genes (STING) | STING1, IRF3, CGAS | TDP1 266/4885SMN1; SMN2 3753/4885LMNA 3267/4885 |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | STING1, IRF3, CGAS | TDP1 266/4885SMN1; SMN2 3753/4885LMNA 3267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.