SCHEMBL825596

SCHEMBL825596

NCCn1cnc2ccccc21

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.78
EGLN3 Q9H6Z9 1/20 0.65
LMNA P02545 7/20 0.64
SMN1; SMN2 Q16637 6/20 0.64
HTT P42858 4/20 0.64
L3MBTL1 Q9Y468 1/20 0.60
CYP11B1 P15538 4/20 0.58
CYP11B2 P19099 4/20 0.58
TNF P01375 1/20 0.58
TSHR P16473 2/20 0.57
NPSR1 Q6W5P4 1/20 0.57
ALOX15 P16050 1/20 0.57
RAB9A P51151 2/20 0.54
GAA P10253 1/20 0.54
MAPK1 P28482 1/20 0.53
NPC1 O15118 2/20 0.53
PKM P14618 1/20 0.53
KDM4E B2RXH2 1/20 0.53
MAPT P10636 1/20 0.53
NFKB1 P19838 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31547778 0.98 TDP1 (0.75) TDP1EGLN3LMNASMN1; SMN2HTT
Hydrochloric Acid SCHEMBL5864330 0.98 TDP1 (0.75) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL86384 0.89 TDP1 (0.72) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL6442808 0.88 TDP1 (1.00) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL6851027 0.87 TDP1 (0.70) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL8654324 0.86 TDP1 (0.68) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL14851019 0.85 TDP1 (0.78) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL30294105 0.84 TDP1 (0.84) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL9814242 0.84 TDP1 (0.84) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL3161153 0.84 TDP1 (0.84) TDP1EGLN3LMNASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119451277-A Cleaning method and texturing method of solar cell texturing cleaning tank 晋能光伏技术有限责任公司 2025-02-14 CN claimed
EP-1802572-B1 INDOL DERIVATIVES AS INHIBITORS OF SOLUBLE ADENYLYL CYCLASE BAYER SCHERING PHARMA AG (DE) 2009-04-22 EP claimed
US-20060074084-A1 Inhibitors of soluble adenylate cyclase BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2006-04-06 US claimed
JP-6329640-A None JP disclosed
EP-3418289-B1 ARTIFICIAL NUCLEOSIDE AND ARTIFICIAL NUCLEOTIDE, AND ARTIFICIAL OLIGONUCLEOTIDE INST OF SCIENCE TOKYO (JP) 2026-04-08 EP disclosed
EP-4710923-A2 INDOLE AHR INHIBITORS AND USES THEREOF Ikena Oncology, Inc. (US) 2026-03-18 EP disclosed
EP-4680236-A2 3-ALKYLAMINE INDOLE ACTIVATORS OF SEROTONIN RECEPTORS ATAI Therapeutics, Inc. (US) 2026-01-21 EP disclosed
EP-4681712-A2 PROCESS FOR THE PRODUCTION OF FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2026-01-21 EP disclosed
EP-3612030-B1 INDOLE AHR INHIBITORS AND USES THEREOF IKENA ONCOLOGY INC (US) 2025-12-24 EP disclosed
EP-4126854-B1 PROCESS FOR THE PRODUCTION OF FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2025-12-03 EP disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
EP-0767792-A1 VITRONECTIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-04-16 EP disclosed
WO-1996000730-A1 VITRONECTIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1996-01-11 WO disclosed
US-5436262-A Pharmacologically active derivatives of 2-(benzimidazol-2-yl)-1,3-diaminopropane DOMPE FARMACEUTICI SPA (IT) 1995-07-25 US disclosed
EP-0630889-A1 Pharmacologically active derivatives of 2-(benzimidazol-2-yl)-1,3-diaminopropane DOMPE' FARMACEUTICI S.p.A. (IT) 1994-12-28 EP disclosed
JP-H06329640-A PHARMACOLOGICALLY ACTIVE DERIVATIVE OF 2-(BENZIMIDAZOLE-2-YL)-1,3-DIAMINOPROPANE DOMPE FARMACEUT SPA 1994-11-29 JP disclosed
US-4434174-A Treating cardiovascular diseases with N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines BERLEX LABORATORIES, INC. (US) 1984-02-28 US disclosed
US-4363808-A N-(3-Phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines BERLEX LABORATORIES, INC. (US) 1982-12-14 US disclosed
EP-0034116-A2 N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines BERLEX LABORATORIES, INC. (US) 1981-08-19 EP disclosed
US-4264494-A Chromium complex dyestuffs for natural polyamides and synthetic nylons BASF AKTIENGESELLSCHAFT (DE) 1981-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS TDP1 3388/4885EGLN3 2598/4885LMNA 3037/4885
US-20060074084-A1 Inhibitors of soluble adenylate cyclase ADCY1, ADCY2, ADCY5 TDP1 857/4885EGLN3 972/4885LMNA 3432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.