Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | KDM6B | O15054 | 1/20 | 0.63 |
| ▸ | KDM5C | P41229 | 1/20 | 0.63 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.63 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.63 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ENO1 | P06733 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinodihydroxamic Acid SCHEMBL940650 | 0.89 | FOLH1 (0.75) | FOLH1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL240068 | 0.78 | — | — | |
| Glutarodihydroxamic Acid SCHEMBL11768782 | 0.76 | HDAC1 (0.81) | FOLH1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL11768749 | 0.76 | HDAC1 (0.93) | FOLH1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL137189 | 0.75 | — | — | |
| SCHEMBL8249763 | 0.75 | — | — | |
| SCHEMBL27643837 | 0.75 | FOLH1 (0.57) | FOLH1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL4572119 | 0.75 | HDAC2 (0.57) | FOLH1KDM4EKDM6BKDM5CEGLN1 | |
| Azelaic Bis Hydroxamic Acid SCHEMBL4741072 | 0.73 | HDAC1 (1.00) | FOLH1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL10439098 | 0.73 | HDAC1 (1.00) | FOLH1KDM4EKDM6BKDM5CEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756825-A | A CHELATING COMPOUND COMPRISES PROTEIN CONJUGATION FUNCTION AND A CHELATE FUNCTION; THE CHELATING COMPOUND IS 3-CARBOXYPROPYL N-(TRIS(2-((N-(BENZYLOXY)AMINO)CARBONYL)ETHYL )-METHYL)SUCCINAMATE | UAB RESEARCH FOUNDATION | 1998-05-26 | — | — | US | claimed |
| US-5756825-A | A CHELATING COMPOUND COMPRISES PROTEIN CONJUGATION FUNCTION AND A CHELATE FUNCTION; THE CHELATING COMPOUND IS 3-CARBOXYPROPYL N-(TRIS(2-((N-(BENZYLOXY)AMINO)CARBONYL)ETHYL )-METHYL)SUCCINAMATE | UAB RESEARCH FOUNDATION | 1998-05-26 | — | — | US | disclosed |