Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516424 | 0.80 | CA2 (0.36) | SMN1; SMN2TSHRMAPTKMT2AHPGD | |
| SCHEMBL5572941 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRMAPTKMT2AHPGD | |
| SCHEMBL1858179 | 0.71 | TSHR (0.36) | SMN1; SMN2TSHRMAPTKMT2AHPGD | |
| SCHEMBL6897874 | 0.71 | FOLH1 (0.43) | SMN1; SMN2TSHRMAPTKMT2A | |
| SCHEMBL176161 | 0.71 | CA2 (0.39) | SMN1; SMN2TSHRMAPTALDH1A1 | |
| SCHEMBL176159 | 0.71 | CA2 (0.39) | SMN1; SMN2TSHRMAPTALDH1A1 | |
| SCHEMBL4236035 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRMAPTKMT2AHPGD | |
| SCHEMBL852878 | 0.70 | TSHR (0.35) | SMN1; SMN2TSHRMAPTKMT2AHPGD | |
| SCHEMBL8994505 | 0.69 | CA2 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL4347265 | 0.69 | MAPT (0.48) | SMN1; SMN2TSHRMAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832851-A1 | Biodegradable poly (amino acids), derivatized amino acid polymers and methods for making the same | Nalco Chemical Company (US) | 1998-04-01 | — | — | EP | claimed |