SCHEMBL8638754

SCHEMBL8638754

O=C(OCCCCCCOC(=O)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.76
LMNA P02545 4/20 0.76
TSHR P16473 3/20 0.76
CYP2D6 P10635 2/20 0.76
SMN1; SMN2 Q16637 2/20 0.76
CYP1A2 P05177 2/20 0.76
MAPK1 P28482 2/20 0.76
CYP2C19 P33261 2/20 0.76
NR1H2 P55055 1/20 0.76
RNASEL Q05823 1/20 0.76
TDP1 Q9NUW8 2/20 0.69
ALDH1A1 P00352 2/20 0.69
CHRM1 P11229 1/20 0.69
SLC6A2 P23975 1/20 0.69
KDR P35968 1/20 0.69
ESR2 Q92731 2/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9674690 1.00 ESR1 (0.76) ESR1LMNATSHRCYP2D6SMN1; SMN2
SCHEMBL10760934 1.00 ESR1 (0.76) ESR1LMNATSHRCYP2D6SMN1; SMN2
SCHEMBL1548913 1.00 ESR1 (0.76) ESR1LMNATSHRCYP2D6SMN1; SMN2
SCHEMBL2880231 0.98 ESR1 (0.79) ESR1LMNATSHRCYP2D6SMN1; SMN2
SCHEMBL8638181 0.94 ESR1 (0.79) ESR1LMNATSHRCYP2D6SMN1; SMN2
SCHEMBL1263536 0.93 ESR1 (0.67) ESR1LMNATSHRCYP2D6SMN1; SMN2
SCHEMBL5155759 0.93 TDP1 (0.79) ESR1LMNATSHRCYP2D6SMN1; SMN2
SCHEMBL105619 0.93 ESR1 (0.67) ESR1LMNATSHRCYP2D6SMN1; SMN2
SCHEMBL5153684 0.93 TDP1 (0.79) ESR1LMNATSHRCYP2D6SMN1; SMN2
SCHEMBL5155888 0.93 TDP1 (0.79) ESR1LMNATSHRCYP2D6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243323-A1 BENZOXAZINE COMPOSITION AND USE THEREOF KANEKA CORPORATION (JP) 2025-07-31 US disclosed
WO-2023038043-A1 BENZOXAZINE COMPOSITION AND USE THEREOF 株式会社カネカ 2023-03-16 WO disclosed
EP-3237487-B1 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS UNIV RUTGERS (US) 2021-02-17 EP disclosed
US-10266647-B2 Biocompatible iodinated diphenol monomers and polymers RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2019-04-23 US disclosed
US-20180291147-A1 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2018-10-11 US disclosed
US-10087285-B2 Biocompatible iodinated diphenol monomers and polymers RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2018-10-02 US disclosed
EP-3237487-A2 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS Rutgers, the State University of New Jersey (US) 2017-11-01 EP disclosed
WO-2016103224-A2 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-06-30 WO disclosed
US-20160177028-A1 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2016-06-23 US disclosed
EP-0605149-B1 Recording sheet JUJO PAPER CO LTD (JP) 1998-04-22 EP disclosed
US-5482913-A CARBONATE TYPE BLOCKED COLOR DEVELOPER, LASER RECORDING NIPPON PAPER INDUSTRIES, CO., LTD. (JP) 1996-01-09 US disclosed
US-5142017-A Optical anisotropy in melt SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-08-25 US disclosed
EP-0410222-A2 Aromatic polyester and a process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10266647-B2 Biocompatible iodinated diphenol monomers and polymers PTGDR, DDT, HPGDS ESR1 483/4885LMNA 4216/4885TSHR 1006/4885
US-20180291147-A1 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS PTGDR, DDT, HPGDS ESR1 483/4885LMNA 4216/4885TSHR 1006/4885
US-10087285-B2 Biocompatible iodinated diphenol monomers and polymers DDT, HPGDS, PTGDR ESR1 647/4885LMNA 4573/4885TSHR 984/4885
US-20160177028-A1 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS DDT, HPGDS, PTGDR ESR1 647/4885LMNA 4573/4885TSHR 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.