SCHEMBL8638773

SCHEMBL8638773

Fc1cccc(Oc2cc(Cl)c(OCC=C(Cl)Cl)c(Cl)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 12/20 0.43
FFAR1 O14842 2/20 0.43
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
MMP9 P14780 1/20 0.35
MMP14 P50281 1/20 0.35
SLC1A5 Q15758 1/20 0.33
KMO O15229 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633049 0.88 HTT (0.33) FFAR4FFAR1
SCHEMBL8653358 0.86 MAOB (0.41) SLC6A2SLC6A4SLC6A3KMO
SCHEMBL8632019 0.86 FFAR4 (0.47) FFAR4FFAR1PPARDPPARA
SCHEMBL8659774 0.84 FFAR1 (0.41) FFAR4FFAR1PPARDPPARA
SCHEMBL8634044 0.82 HSP90AA1 (0.50) FFAR1SLC6A2SLC6A4SLC6A3KMO
SCHEMBL8405986 0.80 MAOB (0.44)
SCHEMBL8635753 0.79 HTT (0.38) FFAR4
SCHEMBL8655532 0.79 FFAR1 (0.40) FFAR4FFAR1PPARDPPARA
SCHEMBL8632980 0.79 MAOB (0.37) SLC6A2SLC6A4SLC6A3MMP14KMO
SCHEMBL8408500 0.78 PTPN7 (0.40) FFAR4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed