SCHEMBL8632019

SCHEMBL8632019

Fc1cccc(Oc2ccc(OCC=C(Cl)Cl)c(Cl)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 10/20 0.47
FFAR1 O14842 2/20 0.47
PPARA Q07869 9/20 0.43
PPARD Q03181 6/20 0.43
PPARG P37231 3/20 0.40
EGFR P00533 1/20 0.37
ERBB2 P04626 1/20 0.37
ERBB3 P21860 1/20 0.37
ERBB4 Q15303 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8638216 0.90 PPARA (0.41) FFAR4FFAR1PPARAPPARDPPARG
SCHEMBL8635559 0.88 PPARA (0.50) PPARAPPARDPPARG
SCHEMBL8634454 0.87 PPARD (0.40) FFAR1PPARAPPARDPPARG
SCHEMBL8638773 0.86 FFAR4 (0.43) FFAR4FFAR1PPARAPPARD
SCHEMBL8635697 0.85 ALDH1A1 (0.46) FFAR1PPARAPPARDEGFRERBB2
SCHEMBL8632081 0.85 PPARD (0.40) PPARAPPARD
SCHEMBL8635410 0.84 HSP90AA1 (0.46) PPARAPPARG
SCHEMBL8635684 0.82 TDP1 (0.42) FFAR1PPARAPPARDPPARG
SCHEMBL8633930 0.81 TDP1 (0.38) PPARAPPARDPPARG
SCHEMBL8636578 0.80 HTR2A (0.41) PPARAPPARDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed