Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.79 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645174 | 0.89 | PTGS2 (1.00) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL9089381 | 0.85 | PTGS2 (0.79) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL16426376 | 0.84 | PTGS2 (0.76) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8953880 | 0.84 | PTGS2 (0.81) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL27531784 | 0.83 | PTGS2 (0.75) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7461840 | 0.82 | PTGS2 (0.81) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7466325 | 0.81 | PTGS2 (0.80) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8925698 | 0.81 | PTGS2 (0.71) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7457684 | 0.81 | PTGS2 (0.74) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8925277 | 0.81 | PTGS2 (0.79) | PTGS2PTGS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856000-A1 | 1,3,5-TRISUBSTITUTED PYRAZOLES FOR TREAMENT OF INFLAMMATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997013755-A1 | 1,3,5-TRISUBSTITUTED PYRAZOLES FOR TREAMENT OF INFLAMMATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-17 | — | — | WO | disclosed |