SCHEMBL8639210

SCHEMBL8639210

CCCCCC([SiH3])CCCCC

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.48
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 2/20 0.43
DNM1 Q05193 2/20 0.43
FDPS P14324 4/20 0.40
GPR84 Q9NQS5 3/20 0.39
SPHK1 Q9NYA1 1/20 0.39
FFAR1 O14842 1/20 0.39
CA1 P00915 1/20 0.39
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7451309 0.97 TSHR (0.50) OPRM1TSHRTHRBLMNADNM1
SCHEMBL10843071 0.97 TSHR (0.50) OPRM1TSHRTHRBLMNADNM1
Octane SCHEMBL1329752 0.97 TSHR (0.50) OPRM1TSHRTHRBLMNADNM1
SCHEMBL527218 0.97 TSHR (0.50) OPRM1TSHRTHRBLMNADNM1
SCHEMBL16209852 0.97 TSHR (0.50) OPRM1TSHRTHRBLMNADNM1
SCHEMBL6246199 0.97 TSHR (0.50) OPRM1TSHRTHRBLMNADNM1
SCHEMBL9342830 0.97 TSHR (0.50) OPRM1TSHRTHRBLMNADNM1
SCHEMBL9206465 0.97 TSHR (0.50) OPRM1TSHRTHRBLMNADNM1
SCHEMBL181209 0.97 TSHR (0.50) OPRM1TSHRTHRBLMNADNM1
SCHEMBL10803629 0.97 TSHR (0.50) OPRM1TSHRTHRBLMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0832047-A1 SILICON CARBOXIDE COMPOSITE REINFORCED WITH CERAMIC FIBERS HAVING A SURFACE ENRICHED IN BORON NITRIDE AlliedSignal Inc. (US) 1998-04-01 EP disclosed
WO-1996041774-A1 SILICON CARBOXIDE COMPOSITE REINFORCED WITH CERAMIC FIBERS HAVING A SURFACE ENRICHED IN BORON NITRIDE ALLIEDSIGNAL INC. (US) 1996-12-27 WO disclosed