Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605732 | 0.84 | MEN1 (0.52) | HTTMEN1KMT2ATSHRHRH3 | |
| SCHEMBL219405 | 0.83 | KMT2A (0.41) | MEN1KMT2ATNK2 | |
| SCHEMBL6468963 | 0.81 | POLB (0.46) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL16982216 | 0.81 | HTT (0.76) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL13220831 | 0.81 | HTT (0.76) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL13289974 | 0.81 | HTT (0.76) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL3278746 | 0.81 | MEN1 (0.40) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL7736990 | 0.81 | MEN1 (0.51) | MEN1KMT2ATSHRTNK2RARB | |
| SCHEMBL13083484 | 0.80 | MEN1 (0.55) | HTTMEN1KMT2ATSHRHRH3 | |
| SCHEMBL14400544 | 0.80 | HTT (0.73) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830440-A1 | LIQUID-CRYSTALLINE POLYMER MATERIAL | Lagerwall, Sven Yngve Torbjörn (SE) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996024648-A1 | LIQUID-CRYSTALLINE POLYMER MATERIAL | LAGERWALL SVEN TORBJOERN (SE) | 1996-08-15 | — | — | WO | disclosed |