SCHEMBL219405

SCHEMBL219405

C=C(C)C(=O)Oc1ccc(-c2ccc(OC3CCCCO3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
ATM Q13315 1/20 0.41
ELANE P08246 1/20 0.41
MEN1 O00255 1/20 0.39
TNK2 Q07912 3/20 0.38
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD11B1 P28845 1/20 0.35
PTPN1 P18031 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20972880 0.96 KMT2A (0.44) KMT2AATMELANEMEN1TNK2
SCHEMBL17754325 0.91 KMT2A (0.37) KMT2AATMELANEMEN1TNK2
SCHEMBL17754341 0.89 APP (0.42) KMT2AATMELANEMEN1TNK2
SCHEMBL22459337 0.88 KMT2A (0.36) KMT2AATMELANEMEN1LMNA
SCHEMBL22109919 0.87 EPHX1 (0.38) KMT2AATMELANEMEN1TNK2
SCHEMBL17754315 0.86 APP (0.43) KMT2AATMMEN1TNK2HSD11B1
SCHEMBL17750863 0.85 APP (0.37) KMT2AATMELANEMEN1TNK2
SCHEMBL8639291 0.83 POLB (0.53) KMT2AMEN1TNK2
SCHEMBL21003911 0.82 MEN1 (0.40) KMT2AMEN1TNK2HSD11B1PTPN1
SCHEMBL3278746 0.81 MEN1 (0.40) KMT2AMEN1LMNASMN1; SMN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160137921-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME DIC CORPORATION (JP) 2016-05-19 US disclosed
US-20160137921-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME DIC CORPORATION (JP) 2016-05-19 US disclosed
US-8089584-B2 Liquid crystal display panel and method for fabricating the same AU OPTRONICS CORP. (TW) 2012-01-03 US disclosed
US-8089584-B2 Liquid crystal display panel and method for fabricating the same AU OPTRONICS CORP. (TW) 2012-01-03 US disclosed
US-8089584-B2 Liquid crystal display panel and method for fabricating the same AU OPTRONICS CORP. (TW) 2012-01-03 US disclosed
US-20100238382-A1 LIQUID CRYSTAL DISPLAY PANEL AND METHOD FOR FABRICATING THE SAME AU OPTRONICS CORP. (TW) 2010-09-23 US disclosed
US-20100238382-A1 LIQUID CRYSTAL DISPLAY PANEL AND METHOD FOR FABRICATING THE SAME AU OPTRONICS CORP. (TW) 2010-09-23 US disclosed
US-20100238382-A1 LIQUID CRYSTAL DISPLAY PANEL AND METHOD FOR FABRICATING THE SAME AU OPTRONICS CORP. (TW) 2010-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160137921-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME RCC1, LPXN, SMC4 KMT2A 2308/4885ATM 3717/4885ELANE 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.