SCHEMBL86396

SCHEMBL86396

O=Cc1ccc(C(=O)O)o1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
POLB P06746 3/20 0.49
LMNA P02545 1/20 0.49
ALDH1A1 P00352 4/20 0.47
TSHR P16473 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
LDHA P00338 1/20 0.45
LDHB P07195 1/20 0.45
HAO1 Q9UJM8 1/20 0.45
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
GAA P10253 1/20 0.42
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
CSF1R P07333 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17495564 1.00 KDM4E (0.52) KDM4ETDP1POLBLMNAALDH1A1
SCHEMBL29952713 0.88 KDM4E (0.59) KDM4ETDP1POLBLMNAALDH1A1
SCHEMBL19206900 0.86 TDP1 (0.47) KDM4ETDP1POLBLMNAALDH1A1
SCHEMBL19206902 0.86 KDM4E (0.41) KDM4ETDP1POLBLMNAALDH1A1
SCHEMBL19206901 0.86 TDP1 (0.47) KDM4ETDP1POLBLMNAALDH1A1
SCHEMBL23828689 0.84 ALDH1A1 (0.48) KDM4ETDP1POLBLMNAALDH1A1
SCHEMBL18911025 0.83 ALDH1A1 (0.44) KDM4ETDP1POLBLMNAALDH1A1
Sumiki'S Acid SCHEMBL28619852 0.83 TDP1 (0.69) KDM4ETDP1POLBALDH1A1TSHR
Aes-103 SCHEMBL28643076 0.82 ALDH1A1 (0.73) KDM4ETDP1POLBLMNAALDH1A1
SCHEMBL9073749 0.80 TDP1 (0.45) TDP1POLBALDH1A1HPGDHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2100 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12371411-B2 Water and thermal treatment of purified 2,5-furandicarboxylic acid Furanix Technologies B, V. (NL) 2025-07-29 US claimed
US-12365660-B2 Organic acid and thermal treatment of purified 2,5-furandicarboxylic acid FURANIX TECHNOLOGIES B.V. (NL) 2025-07-22 US claimed
US-20250223272-A1 COOLING PROCESSES TO PRODUCE ACFC WITH INCREASED CRYSTAL SIZE WITH PURGE EASTMAN CHEMICAL COMPANY (US) 2025-07-10 US claimed
EP-4574988-A1 PROCESS FOR THE PREPARATION OF 2,5-FURANDICARBOXYLIC ACID Annikki GmbH (AT) 2025-06-25 EP claimed
EP-4574987-A1 PROCESS FOR THE PREPARATION OF 2,5-FURANDICARBOXYLIC ACID Annikki GmbH (AT) 2025-06-25 EP claimed
US-12336973-B2 Cancer therapeutic compositions and methods targeting DNAse1L3 PROVIDENCE HEALTH & SERVICES—OREGON (US) 2025-06-24 US claimed
US-20250197367-A1 PROCESS FOR THE OXIDATION OF HYDROXYMETHYLFURFURAL Südzucker AG (DE) 2025-06-19 US claimed
CN-117088833-B Method for preparing formyl-2-furancarboxylic acid from 5-hydroxymethylfurfural 烟台大学 2025-05-30 CN claimed
CN-120041518-A Method for synthesizing furan acid compound by catalyzing 5-hydroxymethylfurfural through chemical enzyme cascade 南京工业大学 2025-05-27 CN claimed
CN-119985789-A Method for simultaneously measuring 5-hydroxymethylfurfural and oxidation products thereof 中国科学院宁波材料技术与工程研究所 2025-05-13 CN claimed
CN-102405207-A Spray process for selective oxidation UNIV KANSAS 2012-04-04 CN claimed
EP-2411357-A2 SPRAY PROCESS FOR SELECTIVE OXIDATION University Of Kansas (US) 2012-02-01 EP claimed
WO-2010111288-A2 SPRAY PROCESS FOR SELECTIVE OXIDATION UNIVERSITY OF KANSAS (US) 2010-09-30 WO claimed
US-7429603-B2 Such as 5-nitro-furan-2-carboxylic acid (2-piperidin-1-yl-phenyl)-amide; diabetes, angiogenesis, psoriasis, restenosis, schizophrenia, rheumatoid arthritis, cardiovascular disease, cancer 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2008-09-30 US claimed
US-7411078-B2 Method for producing furan-2,5-dicarboxylic acid CANON KABUSHIKI KAISHA (JP) 2008-08-12 US claimed
US-20070232815-A1 METHOD FOR PRODUCING FURAN-2,5-DICARBOXYLIC ACID CANON KABUSHIKI KAISHA (JP) 2007-10-04 US claimed
EP-1631560-A2 C-FMS KINASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2006-03-08 EP claimed
US-20050004112-A1 C-fms kinase inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. 2005-01-06 US claimed
WO-2004096795-A2 C-FMS KINASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2004-11-11 WO claimed
EP-0045150-A1 Antibacterial compounds, processes for their preparation and composititions containing them BEECHAM GROUP PLC (GB) 1982-02-03 EP claimed