SCHEMBL8639706

SCHEMBL8639706

[CH2]CCCCCCCC(CC)CCC

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 3/20 0.38
TSHR P16473 2/20 0.38
CA2 P00918 3/20 0.36
L3MBTL1 Q9Y468 1/20 0.32
OPRM1 P35372 1/20 0.32
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA7 P43166 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25182554 1.00 ALDH1A1 (0.39) ALDH1A1TDP1LMNACYP3A4TSHR
SCHEMBL199585 1.00 ALDH1A1 (0.39) ALDH1A1TDP1LMNACYP3A4TSHR
SCHEMBL3094381 1.00 ALDH1A1 (0.39) ALDH1A1TDP1LMNACYP3A4TSHR
SCHEMBL25185567 1.00 ALDH1A1 (0.39) ALDH1A1TDP1LMNACYP3A4TSHR
SCHEMBL6761849 1.00 ALDH1A1 (0.39) ALDH1A1TDP1LMNACYP3A4TSHR
SCHEMBL25185557 1.00 ALDH1A1 (0.39) ALDH1A1TDP1LMNACYP3A4TSHR
SCHEMBL5682734 1.00 ALDH1A1 (0.39) ALDH1A1TDP1LMNACYP3A4TSHR
SCHEMBL199452 0.98 ALDH1A1 (0.41) ALDH1A1TDP1LMNACYP3A4TSHR
SCHEMBL5984758 0.93 ALDH1A1 (0.39) ALDH1A1TDP1LMNACYP3A4TSHR
SCHEMBL5985735 0.93 ALDH1A1 (0.39) ALDH1A1TDP1LMNACYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
WO-2023085299-A1 CATIONIC LIPID 武田薬品工業株式会社 2023-05-19 WO disclosed
EP-3039055-B1 ALIPHATIC POLYCARBONATE-BASED SURFACE ACTIVE AGENTS SASOL CHEMICALS USA LLC (US) 2020-04-15 EP disclosed
CN-105814112-B Surfactant based on aliphatic polycarbonate 萨索尔化学品(美国)有限责任公司 2019-03-08 CN disclosed
US-10011758-B2 Aliphatic polycarbonate-based surface active agents SASOL CHEMICALS (USA) LLC (US) 2018-07-03 US disclosed
US-20160200962-A1 Aliphatic Polycarbonate-Based Surface Active Agents SASOL CHEMICALS (USA) LLC 2016-07-14 US disclosed
EP-3039055-A1 ALIPHATIC POLYCARBONATE-BASED SURFACE ACTIVE AGENTS Sasol Chemicals (USA) LLC (US) 2016-07-06 EP disclosed
WO-2015031348-A1 ALIPHATIC POLYCARBONATE-BASED SURFACE ACTIVE AGENTS SASOL CHEMICALS (USA) LLC (US) 2015-03-05 WO disclosed
EP-0577712-B1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES DU PONT (US) 1998-07-29 EP disclosed
EP-0577712-A1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-01-12 EP disclosed
WO-1992016515-A1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-01 WO disclosed
EP-0002938-B1 NOVEL HETEROCYCLIC CARBOTHIOAMIDES, COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE ELI LILLY AND COMPANY (US) 1982-05-12 EP disclosed
EP-0002939-B1 NOVEL CARBOTHIOAMIDES, COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION ELI LILLY AND COMPANY (US) 1982-04-21 EP disclosed
EP-0003081-B1 THIAZOLIDINECARBOTHIOAMIDES, THEIR PREPARATION, COMPOSITIONS AND USE AS INSECTICIDES ELI LILLY AND COMPANY (US) 1981-12-30 EP disclosed
US-4289778-A SYSTEMIC INSECTICIDES ELI LILLY AND COMPANY (US) 1981-09-15 US disclosed
US-4289766-A Heterocyclic carbothioamides ELI LILLY AND COMPANY (US) 1981-09-15 US disclosed
US-4195092-A INSECTICIDES FOR TREATING MEXICAN BEAN BEETLE ELI LILLY AND COMPANY (US) 1980-03-25 US disclosed
EP-0003081-A2 Thiazolidinecarbothioamides, their preparation, compositions and use as insecticides ELI LILLY AND COMPANY (US) 1979-07-25 EP disclosed
EP-0002939-A2 Novel carbothioamides, compositions containing them and their preparation ELI LILLY AND COMPANY (US) 1979-07-11 EP disclosed
EP-0002938-A2 Novel heterocyclic carbothioamides, compositions containing them, their preparation and use ELI LILLY AND COMPANY (US) 1979-07-11 EP disclosed