SCHEMBL8639963

SCHEMBL8639963

CCCCOCCOCOCCOCCCC

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
CYP3A4 P08684 3/20 0.54
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPT P10636 1/20 0.50
ADRB2 P07550 1/20 0.43
ADRB1 P08588 1/20 0.43
ADRB3 P13945 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
ALDH1A1 P00352 2/20 0.36
RARB P10826 1/20 0.36
CES2 O00748 1/20 0.36
LMNA P02545 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL323671 1.00 TSHR (0.57) TSHRCYP3A4MEN1THRBHTT
SCHEMBL23094079 1.00 TSHR (0.57) TSHRCYP3A4MEN1THRBHTT
SCHEMBL8765586 1.00 TSHR (0.57) TSHRCYP3A4MEN1THRBHTT
SCHEMBL17395919 0.94 TSHR (0.52) TSHRCYP3A4MEN1THRBHTT
SCHEMBL302981 0.94 TSHR (0.55) TSHRCYP3A4MEN1THRBHTT
SCHEMBL8766623 0.92 TSHR (0.50) TSHRCYP3A4MEN1THRBHTT
SCHEMBL27657211 0.92 THRB (0.62) TSHRCYP3A4MEN1THRBHTT
SCHEMBL8334675 0.92 TSHR (0.50) TSHRCYP3A4MEN1THRBHTT
SCHEMBL1647546 0.90 TSHR (0.52) TSHRCYP3A4MEN1THRBHTT
SCHEMBL1133315 0.90 TSHR (0.67) TSHRCYP3A4MEN1THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107239006-B Resist stripping liquid composition, flat plate, method for manufacturing flat plate, and display device 东友精细化工有限公司 2020-09-01 CN claimed
EP-0646557-B1 Fluorination in tubular reactor system MINNESOTA MINING & MFG (US) 1997-08-13 EP claimed
US-5488142-A Fluorination in tubular reactor system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-30 US claimed
EP-0646557-A1 Fluorination in tubular reactor system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-05 EP claimed
EP-0609200-A1 DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-08-10 EP claimed
WO-1990006296-A1 DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-14 WO claimed
CN-107239006-B Resist stripping liquid composition, flat plate, method for manufacturing flat plate, and display device 东友精细化工有限公司 2020-09-01 CN disclosed
US-5753776-A PERFLUORINATION HYDROGEN CONTAINING COMPOUNDS EXFLUOR RESEARCH CORPORATION (US) 1998-05-19 US disclosed
US-5674949-A Liquid-phase fluorination EXFLUOR RESEARCH CORPORATION (US) 1997-10-07 US disclosed
EP-0646557-B1 Fluorination in tubular reactor system MINNESOTA MINING & MFG (US) 1997-08-13 EP disclosed
US-5578278-A TURBULENT FLUID FLOW MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-11-26 US disclosed
US-5571870-A Liquid phase fluorination EXFLUOR RESEARCH CORPORATION (US) 1996-11-05 US disclosed
US-5488142-A Fluorination in tubular reactor system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-30 US disclosed
US-5225550-A PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed
US-5093432-A Perfluorination of esters or ethers EXFLUOR RESEARCH CORPORATION (US) 1992-03-03 US disclosed
EP-0441807-A1 LIQUID PHASE FLUORINATION. EXFLUOR RES CORP (US) 1991-08-21 EP disclosed
EP-0436669-A1 PERFLUOROACETAL AND PERFLUOROKETAL COMPOUNDS AND USE THEREOF IN THERMAL SHOCK TESTING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-07-17 EP disclosed
WO-1990006296-A1 DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-14 WO disclosed
WO-1990003357-A1 PERFLUOROACETAL AND PERFLUOROKETAL COMPOUNDS AND USE THEREOF IN THERMAL SHOCK TESTING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-04-05 WO disclosed
WO-1990003353-A1 LIQUID PHASE FLUORINATION EXFLUOR RESEARCH CORPORATION (US) 1990-04-05 WO disclosed