Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28138192 | 0.91 | ELANE (0.70) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| Water SCHEMBL30474628 | 0.91 | ELANE (0.70) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL9799566 | 0.89 | ELANE (0.72) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| Benzene SCHEMBL28089483 | 0.89 | ELANE (0.72) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL45119 | 0.89 | ELANE (0.72) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| Methane SCHEMBL6301524 | 0.87 | ELANE (0.70) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL8467278 | 0.87 | ELANE (0.70) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL17028724 | 0.87 | ELANE (0.70) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL22042017 | 0.87 | ELANE (0.70) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL31575762 | 0.87 | ELANE (0.70) | ELANEKMT2AESR1HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998034113-A1 | COMBINATORIAL LIBRARIES OF BICYCLIC GUANIDINE DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |