Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640308 | 1.00 | CYP2D6 (0.32) | CYP2D6KMT2A | |
| SCHEMBL575262 | 0.84 | CYP2D6 (0.39) | CYP2D6KMT2A | |
| SCHEMBL8639857 | 0.82 | DRD2 (0.33) | — | |
| SCHEMBL8639861 | 0.82 | DRD2 (0.33) | — | |
| SCHEMBL28161922 | 0.79 | KMT2A (0.41) | CYP2D6KMT2A | |
| SCHEMBL14694085 | 0.73 | CHKA (0.34) | CYP2D6KMT2A | |
| SCHEMBL48580 | 0.73 | — | — | |
| SCHEMBL575183 | 0.73 | — | — | |
| SCHEMBL13915449 | 0.73 | CYP2D6 (0.48) | CYP2D6KMT2A | |
| SCHEMBL1043052 | 0.73 | CYP2D6 (0.48) | CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686143-B1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA GEIGY AG (CH) | 1998-08-12 | — | — | EP | disclosed |
| US-5627215-A | Unsaturate amino compounds for use as anticancer and antiprotozoic agent | CIBA-GEIGY CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0686143-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | Novartis AG (CH) | 1995-12-13 | — | — | EP | disclosed |
| WO-1995018091-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA-GEIGY AG (CH) | 1995-07-06 | — | — | WO | disclosed |