Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5870272 | 1.00 | REN (0.56) | RENSMN1; SMN2ACELMNAMME | |
| SCHEMBL8249019 | 1.00 | REN (0.56) | RENSMN1; SMN2ACELMNAMME | |
| Hydrochloric Acid SCHEMBL10703732 | 0.99 | REN (0.56) | RENSMN1; SMN2ACELMNAMME | |
| Hydrochloric Acid SCHEMBL10703729 | 0.99 | REN (0.56) | RENSMN1; SMN2ACELMNAMME | |
| SCHEMBL8257832 | 0.91 | REN (0.56) | RENSMN1; SMN2ACELMNAABCB11 | |
| SCHEMBL8435225 | 0.91 | REN (0.56) | RENSMN1; SMN2ACELMNAABCB11 | |
| SCHEMBL8248581 | 0.89 | MME (0.62) | ACEMME | |
| SCHEMBL8248814 | 0.89 | MME (0.62) | ACEMME | |
| SCHEMBL8249153 | 0.89 | MME (0.62) | ACEMME | |
| SCHEMBL8248719 | 0.89 | MME (0.62) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |
| EP-0766694-A1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035307-A1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1995-12-28 | — | — | WO | disclosed |
| US-5231084-A | ACE inhibitor | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |