SCHEMBL8640378

SCHEMBL8640378

Cc1ccc(OCCOCCOc2ccc(C)cc2C)c(C)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.63
SMN1; SMN2 Q16637 4/20 0.56
L3MBTL1 Q9Y468 8/20 0.55
MAPT P10636 7/20 0.55
KDM4E B2RXH2 5/20 0.55
KMT2A Q03164 2/20 0.54
NPC1 O15118 1/20 0.54
NFKB1 P19838 1/20 0.54
RAB9A P51151 1/20 0.54
NFKB2 Q00653 1/20 0.54
RELA Q04206 1/20 0.54
TDP1 Q9NUW8 1/20 0.53
S1PR4 O95977 1/20 0.53
MAPK1 P28482 3/20 0.51
HPGD P15428 3/20 0.51
TSHR P16473 1/20 0.51
ALDH1A1 P00352 5/20 0.49
LMNA P02545 2/20 0.49
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891407 0.94 SMN1; SMN2 (0.61) HTR1ASMN1; SMN2L3MBTL1MAPTKDM4E
SCHEMBL15430848 0.93 HTR1A (0.57) HTR1ASMN1; SMN2L3MBTL1MAPTKDM4E
SCHEMBL9011759 0.90 SMN1; SMN2 (0.54) HTR1ASMN1; SMN2L3MBTL1MAPTKDM4E
SCHEMBL9011867 0.87 SMN1; SMN2 (0.59) HTR1ASMN1; SMN2L3MBTL1MAPTKDM4E
SCHEMBL15605970 0.86 TSHR (0.59) HTR1ASMN1; SMN2L3MBTL1MAPTKDM4E
SCHEMBL12180458 0.86 HPGD (0.56) HTR1ASMN1; SMN2L3MBTL1MAPTKDM4E
SCHEMBL9011602 0.85 SMN1; SMN2 (0.57) HTR1ASMN1; SMN2L3MBTL1MAPTKDM4E
SCHEMBL9011659 0.85 SMN1; SMN2 (0.57) HTR1ASMN1; SMN2L3MBTL1MAPTKDM4E
SCHEMBL17815756 0.84 HTR1A (0.50) HTR1ASMN1; SMN2L3MBTL1MAPTKDM4E
SCHEMBL5292022 0.84 SMN1; SMN2 (0.53) HTR1ASMN1; SMN2L3MBTL1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723250-A Process for image formation using liquid developer FUJI XEROX CO., LTD. (JP) 1998-03-03 US disclosed
US-5622804-A COMPOSITION INCLUDING CARRIER COMPRISING ETHER COMPOUND, CHARGE DIRECTOR, DISPERSED TONER PARTICLES COMPRISING INSOLUBLE THERMOPLASTIC RESIN, COLORANT, CHARGE CONTROL AGENT FUJI XEROX CO., LTD. (JP) 1997-04-22 US disclosed
US-5352557-A Ether compound as carrier liquid FUJI XEROX CO., LTD. (JP) 1994-10-04 US disclosed