Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837324 | 0.87 | MAPK1 (0.50) | TDP1MAPK1GABRA1GABRB2CYP3A4 | |
| SCHEMBL28396096 | 0.83 | TDP1 (0.39) | TDP1MAPK1GABRA1GABRB2CYP3A4 | |
| SCHEMBL8093627 | 0.83 | CYP3A4 (0.43) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL11874938 | 0.80 | TDP1 (0.34) | TDP1MAPK1GABRA1GABRB2CYP3A4 | |
| SCHEMBL1493000 | 0.77 | TDP1 (0.48) | TDP1MAPK1GABRA1GABRB2CYP3A4 | |
| SCHEMBL9629412 | 0.75 | TDP1 (0.44) | TDP1MAPK1GABRA1GABRB2CYP3A4 | |
| SCHEMBL1493105 | 0.75 | TDP1 (0.44) | TDP1MAPK1GABRA1GABRB2CYP3A4 | |
| SCHEMBL583613 | 0.74 | GABRA1 (0.42) | TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL8641955 | 0.73 | MAPK1 (0.50) | TDP1MAPK1GABRA1GABRB2CYP3A4 | |
| SCHEMBL1457032 | 0.73 | TDP1 (0.56) | TDP1MAPK1GABRA1GABRB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664014-B1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | AKZO NOBEL NV (NL) | 1998-08-19 | — | — | EP | disclosed |
| EP-0664014-A1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | Akzo Nobel N.V. (NL) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008269-A1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | AKZO NOBEL N.V. (NL) | 1994-04-14 | — | — | WO | disclosed |