SCHEMBL8640451

SCHEMBL8640451

C=CCC1COC(CO)CO1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2872830 0.88 ALDH1A1 (0.46) ALDH1A1TDP1
Ethylene Glycol SCHEMBL17709423 0.86 ALDH1A1 (0.41) ALDH1A1TDP1
SCHEMBL175524 0.85
SCHEMBL334656 0.85
SCHEMBL335471 0.85
Glycidol SCHEMBL27664692 0.83
Water SCHEMBL359935 0.83
Fluoride SCHEMBL28170948 0.83
Glycidol SCHEMBL15367861 0.80
SCHEMBL13838050 0.80 TDP1 (0.56) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744459-A ANTITUMOR AGENTS UNIVERSITY OF CONNECTICUT (US) 1998-04-28 US disclosed
US-5489580-A ANTITUMOR AGENTS AND IMMUNO MODULATORS UNIVERSITY OF CONNECTICUT (US) 1996-02-06 US disclosed