SCHEMBL8640494

SCHEMBL8640494

O=C(O)C=CCc1c2ccc(=O)cc-2oc2cc(O)ccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.54
▸ MEN1 O00255 3/20 0.54
▸ KMT2A Q03164 3/20 0.54
▸ POLB P06746 2/20 0.54
▸ ATM Q13315 1/20 0.54
▸ PLEC Q15149 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ CDC25A P30304 1/20 0.48
▸ CDC25B P30305 1/20 0.48
▸ CDC25C P30307 1/20 0.48
▸ ALPL P05186 1/20 0.48
▸ ALPI P09923 1/20 0.48
▸ ALPG P10696 1/20 0.48
▸ GNG2 P59768 1/20 0.46
▸ GNB1 P62873 1/20 0.46
▸ ESR1 P03372 9/20 0.43
▸ DNASE1L3 Q13609 1/20 0.41
▸ PRMT1 Q99873 1/20 0.41
▸ HPGD P15428 2/20 0.41
▸ TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2777627 0.80 HPGD (0.60) USP2MEN1KMT2APOLBATM
SCHEMBL2792422 0.80 USP2 (0.57) USP2MEN1KMT2APOLBATM
SCHEMBL2792418 0.80 USP2 (0.57) USP2MEN1KMT2APOLBATM
SCHEMBL23861287 0.79 USP2 (0.59) USP2MEN1KMT2APOLBATM
SCHEMBL16019277 0.79 USP2 (0.59) USP2MEN1KMT2APOLBATM
SCHEMBL23861283 0.76 USP2 (0.55) USP2MEN1KMT2APOLBATM
SCHEMBL8427558 0.75 USP2 (0.64) USP2MEN1KMT2APOLBATM
SCHEMBL14596237 0.74 USP2 (0.57) USP2MEN1KMT2APOLBATM
SCHEMBL15984334 0.73 LCK (0.64) KMT2ACDC25ACDC25CKDM4EALDH1A1
SCHEMBL2775968 0.72 USP2 (0.63) USP2MEN1KMT2APOLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0252683-B1 Process and reagents for DNA sequence analysis DU PONT (US) 1995-01-18 — — EP claimed
EP-0252683-A2 Process and reagents for DNA sequence analysis E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-13 — — EP claimed
JP-10158530-A — — None — — JP disclosed
JP-9124636-A — — None — — JP disclosed
JP-H10158530-A FLUORESCENT DYE AND ITS PRODUCTION E I DU PONT DE NEMOURS & CO 1998-06-16 — — JP disclosed
JP-H09124636-A FLUORESCENT DYE E I DU PONT DE NEMOURS & CO 1997-05-13 — — JP disclosed
EP-0252683-B1 Process and reagents for DNA sequence analysis DU PONT (US) 1995-01-18 — — EP disclosed
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