Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP7 | P09237 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | ECE1 | P42892 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23522672 | 0.81 | SHBG (0.50) | SHBGALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL29016515 | 0.79 | SHBG (0.46) | SHBGALDH1A1CA1CA2EPHX1 | |
| SCHEMBL27857861 | 0.74 | EPHX1 (0.38) | CA1CA2EPHX1 | |
| SCHEMBL19175664 | 0.74 | SHBG (0.43) | SHBGALDH1A1EPHX1SMN1; SMN2MMP1 | |
| SCHEMBL7761672 | 0.73 | SHBG (0.52) | SHBGALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL1094949 | 0.73 | SHBG (0.52) | SHBGALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL14236531 | 0.73 | EPHX1 (0.39) | SHBGALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL28112002 | 0.73 | SHBG (0.39) | SHBGCA1CA2EPHX1CA12 | |
| SCHEMBL13798128 | 0.72 | SHBG (0.41) | SHBGALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL20600342 | 0.72 | SHBG (0.41) | SHBGALDH1A1EPHX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999043285-A2 | SULPHONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1999-09-02 | — | — | WO | disclosed |