Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558101 | 1.00 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL6050828 | 1.00 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL10891279 | 1.00 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL2569149 | 1.00 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL8640554 | 1.00 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL2229452 | 1.00 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL286072 | 1.00 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL3658217 | 1.00 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL4712511 | 1.00 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL157427 | 0.98 | CYP2D6 (0.33) | CYP2D6MEN1KMT2ALMNAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760011-A | USEFUL AGAINST BACTERIAL AND MYCOPLASMIC PATHOGENS | PFIZER INC. (US) | 1998-06-02 | — | — | US | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-4629786-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1986-12-16 | — | — | US | disclosed |
| US-4546188-A | USEFUL IN TREATMENT OF PEPTIC ULCERS | BRISTOL-MYERS COMPANY (US) | 1985-10-08 | — | — | US | disclosed |