Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919318 | 0.93 | HTT (0.44) | SMN1; SMN2MAPTALDH1A1HTTCYP3A4 | |
| SCHEMBL8641624 | 0.90 | MAPT (0.46) | SMN1; SMN2MAPTALDH1A1HTTNPC1 | |
| SCHEMBL9088185 | 0.88 | EGFR (0.50) | SMN1; SMN2MAPTALDH1A1HTTNPC1 | |
| SCHEMBL6755732 | 0.87 | MAPT (0.42) | SMN1; SMN2MAPTALDH1A1HTTCYP3A4 | |
| SCHEMBL8920720 | 0.85 | MAPT (0.41) | SMN1; SMN2MAPTALDH1A1HTTCYP3A4 | |
| SCHEMBL8920097 | 0.85 | CYP3A4 (0.44) | SMN1; SMN2MAPTALDH1A1HTTCYP3A4 | |
| SCHEMBL1026866 | 0.84 | KDM4E (0.45) | SMN1; SMN2MAPTALDH1A1HTTCYP3A4 | |
| SCHEMBL6755855 | 0.83 | HTT (0.47) | SMN1; SMN2MAPTALDH1A1HTTCYP3A4 | |
| SCHEMBL8922319 | 0.82 | MAPT (0.43) | SMN1; SMN2MAPTALDH1A1HTTCYP3A4 | |
| SCHEMBL9087932 | 0.82 | MAPT (0.48) | SMN1; SMN2MAPTALDH1A1NR1H4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5718731-A | Oxidation hair dye composition based on 4,5-diaminopyrazole and m-phenylenediamine derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |
| EP-0692245-B1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | WELLA AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| US-5534267-A | Composition for the oxidative dyeing of hair containing 4,5-diaminopyrazole derivatives as well as new 4,5-diaminopyrazole derivatives and process for their synthesis | WELLA AKTIENGESELLSCHAFT (DE) | 1996-07-09 | — | — | US | disclosed |
| EP-0692245-A1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | Wella Aktiengesellschaft (DE) | 1996-01-17 | — | — | EP | disclosed |
| EP-0618903-A1 | OXIDATION HAIR DYE CONTAINING 4,5-DIAMINOPYRAZOLE DERIVATIVES AND NOVEL 4,5-DIAMINOPYRAZOLE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | Wella Aktiengesellschaft (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1994008970-A1 | OXIDATION HAIR DYE CONTAINING 4,5-DIAMINOPYRAZOLE DERIVATIVES AND NOVEL 4,5-DIAMINOPYRAZOLE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | WELLA AKTIENGESELLSCHAFT (DE) | 1994-04-28 | — | — | WO | disclosed |