Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919318 | 0.90 | HTT (0.44) | MAPTKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9087932 | 0.90 | MAPT (0.48) | EGFRMAPTNPSR1MAPK1SMN1; SMN2 | |
| SCHEMBL8640609 | 0.88 | SMN1; SMN2 (0.50) | MAPTNPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8641624 | 0.87 | MAPT (0.46) | MAPTNPSR1NPC1RAB9AKDM4E | |
| SCHEMBL6755732 | 0.85 | MAPT (0.42) | EGFRMAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL9089433 | 0.85 | RAB9A (0.47) | EGFRMAPTNPC1RAB9AKDM4E | |
| SCHEMBL9089099 | 0.84 | SMN1; SMN2 (0.43) | EGFRMAPTNPC1RAB9AKDM4E | |
| SCHEMBL5416063 | 0.83 | KDM4E (0.43) | EGFRMAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL8920720 | 0.82 | MAPT (0.41) | MAPTMAPK1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8920097 | 0.82 | CYP3A4 (0.44) | MAPTKDM4EMAPK1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534267-A | Composition for the oxidative dyeing of hair containing 4,5-diaminopyrazole derivatives as well as new 4,5-diaminopyrazole derivatives and process for their synthesis | WELLA AKTIENGESELLSCHAFT (DE) | 1996-07-09 | — | — | US | disclosed |
| EP-0618903-A1 | OXIDATION HAIR DYE CONTAINING 4,5-DIAMINOPYRAZOLE DERIVATIVES AND NOVEL 4,5-DIAMINOPYRAZOLE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | Wella Aktiengesellschaft (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1994008970-A1 | OXIDATION HAIR DYE CONTAINING 4,5-DIAMINOPYRAZOLE DERIVATIVES AND NOVEL 4,5-DIAMINOPYRAZOLE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | WELLA AKTIENGESELLSCHAFT (DE) | 1994-04-28 | — | — | WO | disclosed |