Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.79 |
| ▸ | RAB9A | P51151 | 8/20 | 0.79 |
| ▸ | MEN1 | O00255 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.79 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640680 | 1.00 | NPC1 (0.79) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8637284 | 0.89 | MEN1 (0.65) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8637280 | 0.89 | MEN1 (0.65) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2849668 | 0.88 | TRPA1 (1.00) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2849664 | 0.88 | TRPA1 (1.00) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16215175 | 0.88 | NPC1 (0.76) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8637121 | 0.86 | MEN1 (0.69) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8637112 | 0.86 | MEN1 (0.69) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8635549 | 0.86 | KMT2A (0.70) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8635541 | 0.86 | KMT2A (0.70) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |