Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639139 | 0.88 | EPHX2 (0.40) | EPHX2GAA | |
| SCHEMBL8583428 | 0.84 | KCNH3 (0.32) | — | |
| SCHEMBL8639052 | 0.80 | NOX1 (0.43) | GAASMN1; SMN2 | |
| SCHEMBL8584256 | 0.80 | MAPT (0.38) | GAAHTTSMN1; SMN2 | |
| SCHEMBL8637571 | 0.79 | LRRK2 (0.34) | — | |
| SCHEMBL16974920 | 0.79 | KMT2A (0.47) | GAAHTTSMN1; SMN2 | |
| SCHEMBL16974892 | 0.77 | EPHX2 (0.36) | EPHX2HTTSMN1; SMN2 | |
| SCHEMBL8639320 | 0.77 | LRRK2 (0.38) | HTTSMN1; SMN2 | |
| SCHEMBL2344742 | 0.77 | GLP1R (0.31) | — | |
| SCHEMBL16974832 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099304-A1 | NOVEL THERAPEUTICS FOR THE TREATMENT OF GLAUCOMA | Mayo Foundation for Medical Education and Research (US) | 2016-12-07 | — | — | EP | disclosed |
| WO-2015117024-A1 | NOVEL THERAPEUTICS FOR THE TREATMENT OF GLAUCOMA | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2015-08-06 | — | — | WO | disclosed |
| EP-0906297-A1 | 1,2,4-BENZOTHIADIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997049692-A1 | 1,2,4-BENZOTHIADIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-12-31 | — | — | WO | disclosed |