Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.66 |
| ▸ | HTR3A | P46098 | 2/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | HTR1D | P28221 | 1/20 | 0.66 |
| ▸ | HTR1B | P28222 | 1/20 | 0.66 |
| ▸ | HTR1E | P28566 | 1/20 | 0.66 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | HTR5A | P47898 | 1/20 | 0.66 |
| ▸ | HTR6 | P50406 | 1/20 | 0.66 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5584592 | 0.91 | HTR2A (0.54) | HTR2AHTR3AHTR1AHTR1DHTR1B | |
| SCHEMBL3648073 | 0.86 | PDE4B (0.78) | HTR2AHTR3AHTR1AHTR1DHTR1B | |
| SCHEMBL25309520 | 0.82 | QDPR (0.45) | HTR2AHTR3AHTR1AHTR1DHTR1B | |
| SCHEMBL13698213 | 0.82 | PDE4B (0.64) | HTR2AHTR3AHTR1AHTR1DHTR1B | |
| SCHEMBL13093036 | 0.80 | SLC6A2 (0.81) | HTR2AHTR3AHTR1AHTR1DHTR1B | |
| SCHEMBL1823096 | 0.80 | SLC6A2 (0.81) | HTR2AHTR3AHTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL27410631 | 0.79 | SLC6A2 (0.78) | HTR2AHTR3AHTR1AHTR1DHTR1B | |
| SCHEMBL27847654 | 0.79 | PDE4B (0.64) | HTR2AHTR3AHTR1AHTR1DHTR1B | |
| SCHEMBL27864745 | 0.79 | PDE4B (0.64) | HTR2AHTR3AHTR1AHTR1DHTR1B | |
| SCHEMBL30291084 | 0.78 | PDE4B (1.00) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |