Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | QDPR | P09417 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2709718 | 0.89 | HTR2C (0.59) | HTR2CQDPR | |
| Hydrochloric Acid SCHEMBL4881862 | 0.87 | HTR2C (0.61) | HTR2CQDPR | |
| SCHEMBL13698229 | 0.84 | HTR3A (0.54) | HTR3APDE4BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL13698222 | 0.84 | HTR3A (0.50) | HTR3APDE4BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL826383 | 0.84 | SLC6A2 (0.63) | HTR3APDE4BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL25558703 | 0.84 | SLC6A2 (0.49) | CYP2D6SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL18617806 | 0.82 | HTR3A (0.47) | HTR3APDE4BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL9482386 | 0.80 | HTR3A (0.46) | HTR3APDE4BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL614331 | 0.79 | HTR3A (0.45) | HTR3APDE4BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL15508750 | 0.79 | HTR3A (0.66) | HTR3APDE4BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |