Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638733 | 1.00 | EGFR (0.42) | EGFRSRCJAK2JAK1PARP1 | |
| SCHEMBL8300349 | 1.00 | EGFR (0.42) | EGFRSRCJAK2JAK1PARP1 | |
| SCHEMBL8639265 | 0.88 | SRC (0.43) | EGFRSRCGPR119MAPT | |
| SCHEMBL8304914 | 0.88 | SRC (0.43) | EGFRSRCGPR119MAPT | |
| SCHEMBL8639604 | 0.76 | USP30 (0.44) | EGFRSRCJAK2JAK1L3MBTL1 | |
| SCHEMBL14193 | 0.72 | SRC (0.44) | EGFRSRCPARP1MAPT | |
| SCHEMBL16707781 | 0.71 | JAK2 (0.53) | JAK2JAK1GPR119 | |
| SCHEMBL31085811 | 0.71 | SMN1; SMN2 (0.55) | JAK2JAK1PARP1L3MBTL1GPR119 | |
| SCHEMBL21069737 | 0.71 | SMN1; SMN2 (0.55) | JAK2JAK1PARP1L3MBTL1GPR119 | |
| SCHEMBL22609548 | 0.71 | SMN1; SMN2 (0.55) | JAK2JAK1PARP1L3MBTL1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849893-A | Nucleic acid-binding oligomers possessing C-branching for therapy and diagnostics | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |