Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300349 | 0.76 | EGFR (0.42) | L3MBTL1MAPTMAPK1NPSR1GPR119 | |
| SCHEMBL8638733 | 0.76 | EGFR (0.42) | L3MBTL1MAPTMAPK1NPSR1GPR119 | |
| SCHEMBL8640829 | 0.76 | EGFR (0.42) | L3MBTL1MAPTMAPK1NPSR1GPR119 | |
| SCHEMBL9230276 | 0.72 | POLB (0.46) | ABL1RIN1KDM4EPKMSRC | |
| SCHEMBL9230285 | 0.71 | POLB (0.47) | USP30ABL1RIN1KDM4EPKM | |
| SCHEMBL9230291 | 0.70 | ABL1 (0.41) | ABL1RIN1SRCPOLB | |
| SCHEMBL9230690 | 0.70 | ABCB1 (0.40) | ABL1RIN1SRCPOLBALDH1A1 | |
| SCHEMBL7532354 | 0.69 | POLB (0.42) | ABL1RIN1KDM4EPKMSRC | |
| SCHEMBL8304924 | 0.69 | POLB (0.44) | ABL1RIN1KDM4EPKMSRC | |
| SCHEMBL9230297 | 0.69 | ABL1 (0.40) | ABL1RIN1GPR119SRCPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849893-A | Nucleic acid-binding oligomers possessing C-branching for therapy and diagnostics | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |