SCHEMBL8640960

SCHEMBL8640960

CCCCCCCCCCC1C=CC(c2ccc(F)c(F)c2)=CC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.35
PDE5A O76074 1/20 0.32
RARB P10826 2/20 0.32
RARA P10276 1/20 0.32
RARG P13631 1/20 0.32
GRM2 Q14416 1/20 0.32
MGLL Q99685 5/20 0.30
FAAH O00519 2/20 0.30
CNR1 P21554 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8638593 1.00 GCGR (0.35) GCGRPDE5ARARBRARARARG
SCHEMBL8642885 1.00 GCGR (0.35) GCGRPDE5ARARBRARARARG
SCHEMBL8638023 1.00 GCGR (0.35) GCGRPDE5ARARBRARARARG
SCHEMBL8640142 1.00 GCGR (0.35) GCGRPDE5ARARBRARARARG
SCHEMBL8638046 0.99 GCGR (0.36) GCGRPDE5ARARBRARARARG
SCHEMBL8635282 0.95 GCGR (0.34) GCGRPDE5A
SCHEMBL8638430 0.89 GCGR (0.30) GCGR
SCHEMBL8637039 0.85 GRM2 (0.37) GCGRGRM2
SCHEMBL8640877 0.85 GRM2 (0.37) GCGRGRM2
SCHEMBL8636705 0.85 GRM2 (0.37) GCGRGRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571652-B1 Liquid crystalline substituted dihydrobenzene derivatives CITIZEN WATCH CO LTD (JP) 1998-08-05 EP disclosed
US-5342546-A Liquid crystal compositions L.C.C. CONSULTANTS CO., LTD. (JP) 1994-08-30 US disclosed
EP-0571652-A1 Liquid crystalline substituted dihydrobenzene derivatives L.C.C. CONSULTANTS CO., LTD. (JP) 1993-12-01 EP disclosed