Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 8/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640995 | 1.00 | GRM2 (0.37) | GRM2PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL8637984 | 1.00 | GRM2 (0.37) | GRM2PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL8640877 | 1.00 | GRM2 (0.37) | GRM2PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL8637039 | 1.00 | GRM2 (0.37) | GRM2PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL8636477 | 0.99 | GRM2 (0.35) | GRM2PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL8638145 | 0.94 | PSMD14 (0.31) | GRM2PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL8636717 | 0.88 | ALDH1A1 (0.30) | GAA | |
| SCHEMBL8638473 | 0.87 | GRM2 (0.36) | GRM2GCGRTLR8 | |
| SCHEMBL8643070 | 0.87 | GRM2 (0.36) | GRM2GCGRTLR8 | |
| SCHEMBL8639841 | 0.87 | GRM2 (0.36) | GRM2GCGRTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |