Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.69 |
| ▸ | CPB1 | P15086 | 1/20 | 0.69 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.69 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.62 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.59 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14519208 | 1.00 | FOLH1 (0.69) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14157462 | 0.98 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL18907025 | 0.98 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL18907028 | 0.98 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14157482 | 0.98 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14157463 | 0.98 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL16782306 | 0.93 | SIRT2 (0.66) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL464715 | 0.93 | FOLH1 (0.78) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL4561005 | 0.93 | FOLH1 (0.78) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL806151 | 0.93 | FOLH1 (0.78) | FOLH1CPB1CPB2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832150-A1 | CASCADE POLYMERS WITH IODINE-CONTAINING AROMATIC COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041830-A1 | CASCADE POLYMERS WITH IODINE-CONTAINING AROMATIC COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-12-27 | — | — | WO | disclosed |