SCHEMBL806151

SCHEMBL806151

O=C(NCCCCC(NC(=O)OCc1ccccc1)C(=O)O)OCc1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.78
SIRT2 Q8IXJ6 1/20 0.69
SIRT1 Q96EB6 1/20 0.69
MMP2 P08253 2/20 0.67
MMP9 P14780 2/20 0.67
ITGB3 P05106 1/20 0.64
ITGAV P06756 1/20 0.64
CPB1 P15086 1/20 0.64
CPB2 Q96IY4 1/20 0.64
TGM2 P21980 3/20 0.64
SIRT5 Q9NXA8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4561005 1.00 FOLH1 (0.78) FOLH1SIRT2SIRT1MMP2MMP9
SCHEMBL464715 1.00 FOLH1 (0.78) FOLH1SIRT2SIRT1MMP2MMP9
SCHEMBL11875673 0.96 FOLH1 (0.72) FOLH1SIRT2SIRT1MMP2MMP9
SCHEMBL4173693 0.96 FOLH1 (0.72) FOLH1SIRT2SIRT1MMP2MMP9
SCHEMBL4173691 0.96 FOLH1 (0.72) FOLH1SIRT2SIRT1MMP2MMP9
SCHEMBL18907025 0.95 FOLH1 (0.72) FOLH1SIRT2SIRT1MMP2MMP9
SCHEMBL14157463 0.95 FOLH1 (0.72) FOLH1SIRT2SIRT1MMP2MMP9
SCHEMBL18907028 0.95 FOLH1 (0.72) FOLH1SIRT2SIRT1MMP2MMP9
SCHEMBL14157482 0.95 FOLH1 (0.72) FOLH1SIRT2SIRT1MMP2MMP9
SCHEMBL14157462 0.95 FOLH1 (0.72) FOLH1SIRT2SIRT1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO claimed
CN-112110834-A Modified hydrophobic auxiliary material and preparation method and application thereof 浙江智达药业有限公司 2020-12-22 CN claimed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
CN-119192214-B Targeted binding fibroblast activation protein multimeric compound and application thereof 杭州景嘉航生物医药科技有限公司 2025-04-01 CN disclosed
CN-119192214-A Targeted binding fibroblast activation protein multimeric compound and application thereof 杭州景嘉航生物医药科技有限公司 2024-12-27 CN disclosed
EP-3988538-B1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO LTD (CN) 2024-08-07 EP disclosed
US-20230141981-A1 NOVEL COMPOUNDS AND COMPOSITION FOR TARGETED THERAPY OF KIDNEY-ASSOCIATED CANCERS Shanghai MICURX Pharmaceuticals Co., Ltd. (CN) 2023-05-11 US disclosed
CN-115298198-A Novel compounds and compositions for targeted therapy of kidney-related cancers 上海盟科药业股份有限公司 2022-11-04 CN disclosed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP disclosed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US disclosed
US-20090048166-A1 NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR AFFYMAX, INC. (US) 2009-02-19 US disclosed
US-20080213187-A1 NOVEL CASCADE POLYMER COMPLEXES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM EPIX PHARMACEUTICALS, INC. 2008-09-04 US disclosed
US-7414105-B2 Peptide dimer bonded to polyethylene glycol through amide groups; insufficient or defective red blood cell production AFFYMAX, INC. (US) 2008-08-19 US disclosed
US-7414105-B2 Peptide dimer bonded to polyethylene glycol through amide groups; insufficient or defective red blood cell production AFFYMAX, INC. (US) 2008-08-19 US disclosed
US-20080081783-A1 ERYTHROPOIETIN RECEPTOR PEPTIDE FORMULATIONS AND USES AFFYMAX, INC. (US) 2008-04-03 US disclosed
US-20080081783-A1 ERYTHROPOIETIN RECEPTOR PEPTIDE FORMULATIONS AND USES AFFYMAX, INC. (US) 2008-04-03 US disclosed
US-20070104704-A1 Erythropoietin receptor peptide formulations and uses AFFYMAX, INC. (US) 2007-05-10 US disclosed
US-20070104704-A1 Erythropoietin receptor peptide formulations and uses AFFYMAX, INC. (US) 2007-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP FOLH1 4283/4885SIRT2 2667/4885SIRT1 3042/4885
US-20090048166-A1 NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR EPOR, PROKR1, EDNRB FOLH1 722/4885SIRT2 4336/4885SIRT1 4168/4885
US-20080213187-A1 NOVEL CASCADE POLYMER COMPLEXES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PGF, F13A1, F11 FOLH1 2308/4885SIRT2 4034/4885SIRT1 3432/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 FOLH1 3754/4885SIRT2 2590/4885SIRT1 2095/4885
US-20080081783-A1 ERYTHROPOIETIN RECEPTOR PEPTIDE FORMULATIONS AND USES EPOR, PROKR1, PROKR2 FOLH1 772/4885SIRT2 3424/4885SIRT1 3110/4885
US-20070104704-A1 Erythropoietin receptor peptide formulations and uses EPOR, PROKR1, PROKR2 FOLH1 772/4885SIRT2 3424/4885SIRT1 3110/4885
US-20230141981-A1 NOVEL COMPOUNDS AND COMPOSITION FOR TARGETED THERAPY OF KIDNEY-ASSOCIATED CANCERS GLS, ATP6V1B1, KRAS FOLH1 163/4885SIRT2 3220/4885SIRT1 3292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.