Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.73 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641123 | 0.95 | TDP1 (0.71) | TDP1TSHRL3MBTL1GAAMAPK1 | |
| Trifluoroacetic Acid SCHEMBL27989854 | 0.91 | TDP1 (0.60) | TDP1TSHRL3MBTL1GAAMAPK1 | |
| SCHEMBL8637116 | 0.90 | TDP1 (0.67) | TDP1TSHRL3MBTL1MAPK1TP53 | |
| SCHEMBL8637734 | 0.85 | SCN1A (0.69) | TDP1TSHRL3MBTL1MAPK1TP53 | |
| SCHEMBL9765812 | 0.85 | TDP1 (0.92) | TDP1TSHRL3MBTL1MAPK1TP53 | |
| SCHEMBL12083356 | 0.85 | TDP1 (1.00) | TDP1TSHRL3MBTL1MAPK1TP53 | |
| SCHEMBL29408707 | 0.83 | TDP1 (0.89) | TDP1TSHRL3MBTL1MAPK1TP53 | |
| Ammonia Solution, Strong SCHEMBL11053275 | 0.83 | TDP1 (0.96) | TDP1TSHRL3MBTL1MAPK1TP53 | |
| SCHEMBL15397549 | 0.83 | TDP1 (0.89) | TDP1TSHRL3MBTL1MAPK1TP53 | |
| SCHEMBL6414201 | 0.83 | TDP1 (0.61) | TDP1TSHRL3MBTL1MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104168958-B | Diaryl sulfonamides useful for the treatment of inflammation and cancer | 坎塞拉有限公司 | 2017-12-01 | — | — | CN | claimed |
| US-4298603-A | LOCAL ANESTHETICS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1981-11-03 | — | — | US | claimed |
| CN-104168958-B | Diaryl sulfonamides useful for the treatment of inflammation and cancer | 坎塞拉有限公司 | 2017-12-01 | — | — | CN | disclosed |
| US-5753407-A | Polyamic acid composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5585217-A | Polyamic acid composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-12-17 | — | — | US | disclosed |
| US-4298603-A | LOCAL ANESTHETICS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1981-11-03 | — | — | US | disclosed |
| EP-0031632-A1 | O-Aminoalkylsalicylates, process for their preparation, and their pharmaceutical compositions | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1981-07-08 | — | — | EP | disclosed |