Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 4/20 | 0.69 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.69 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644412 | 0.96 | TDP1 (0.67) | SCN1ASCN2ASCN3ATDP1TSHR | |
| Detanosal SCHEMBL2110875 | 0.91 | SCN1A (0.68) | SCN1ASCN2ASCN3ATDP1TSHR | |
| Detanosal SCHEMBL30397539 | 0.90 | SCN1A (0.66) | SCN1ASCN2ASCN3ATDP1TSHR | |
| Detanosal SCHEMBL29163805 | 0.90 | SCN1A (0.66) | SCN1ASCN2ASCN3ATDP1TSHR | |
| Detanosal SCHEMBL27797753 | 0.87 | SCN1A (0.67) | SCN1ASCN2ASCN3ATDP1TSHR | |
| SCHEMBL8642191 | 0.85 | TDP1 (0.73) | SCN1ASCN2ASCN3ATDP1TSHR | |
| SCHEMBL9401308 | 0.84 | TDP1 (0.62) | SCN1ASCN2ASCN3ATDP1TSHR | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL29421150 | 0.83 | TSHR (0.80) | TDP1TSHRL3MBTL1CYP3A4TP53 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL62565 | 0.83 | TSHR (0.80) | TDP1TSHRL3MBTL1CYP3A4TP53 | |
| SCHEMBL12083356 | 0.82 | TDP1 (1.00) | TDP1TSHRL3MBTL1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753407-A | Polyamic acid composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5585217-A | Polyamic acid composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-12-17 | — | — | US | disclosed |
| US-4298603-A | LOCAL ANESTHETICS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1981-11-03 | — | — | US | disclosed |
| EP-0031632-A1 | O-Aminoalkylsalicylates, process for their preparation, and their pharmaceutical compositions | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1981-07-08 | — | — | EP | disclosed |