SCHEMBL86434

SCHEMBL86434

O=C1CCOc2cc3c(cc21)SCCC3=O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
MAOB P27338 12/20 0.47
VHL P40337 1/20 0.47
ELOC Q15369 1/20 0.47
ELOB Q15370 1/20 0.47
MAOA P21397 1/20 0.47
HTT P42858 1/20 0.44
GRM5 P41594 7/20 0.41
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CA2 P00918 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL86805 0.83 MAOB (0.62) ALDH1A1MAOBMAOAGRM5NPC1
SCHEMBL86320 0.81 KDM4E (0.51) KDM4EALDH1A1MAOBVHLELOC
SCHEMBL86325 0.74 MAOB (0.53) KDM4EALDH1A1MAOBMAOAGRM5
SCHEMBL18655347 0.73 KDM4E (0.47) KDM4EALDH1A1VHLELOCELOB
SCHEMBL13871428 0.73 MAOB (0.51) ALDH1A1MAOBMAOAGRM5NPC1
SCHEMBL10364205 0.71 VHL (0.62) KDM4EALDH1A1VHLELOCELOB
SCHEMBL1694551 0.71 MAOB (0.53) ALDH1A1MAOBMAOAGRM5NPC1
SCHEMBL9607758 0.71 KDM4E (0.56) KDM4EALDH1A1MAOBVHLELOC
SCHEMBL10363739 0.71 KDM4E (0.56) KDM4EALDH1A1VHLELOCELOB
SCHEMBL16333591 0.71 MAOB (0.62) ALDH1A1MAOBMAOAGRM5NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
EP-3950856-A1 PHOTOCURABLE INK COMPOSITION AND METHOD FOR IMAGE RECORDING FUJIFILM Corporation (JP) 2022-02-09 EP disclosed
US-20210395549-A1 PHOTOCURABLE INK COMPOSITION AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2021-12-23 US disclosed
EP-3689981-A1 ACTINIC-RAY-CURABLE INK-JET INK, LIGHT-SHIELDING FILM, AND PRODUCTION METHOD FOR LIGHT-SHIELDING FILM FUJIFILM Corporation (JP) 2020-08-05 EP disclosed
US-20200199385-A1 ACTIVE ENERGY RAY CURABLE-TYPE INK JET INK, LIGHT SHIELDING FILM, AND METHOD OF MANUFACTURING LIGHT SHIELDING FILM FUJIFILM CORPORATION (JP) 2020-06-25 US disclosed
EP-2502967-B1 Ink composition FUJIFILM SPECIALITY INK SYSTEMS LTD (GB) 2019-08-21 EP disclosed
EP-2412768-B1 Inkjet ink composition, inkjet recording method, and printed material FUJIFILM CORP (JP) 2019-01-23 EP disclosed
US-20100015352-A1 INK-JET INK COMPOSITION, AND INK-JET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-01-21 US disclosed
EP-2145931-A1 Photo-curable composition, ink composition, and inkjet recording method using the ink composition Fujifilm Corporation (JP) 2010-01-20 EP disclosed
US-20090087576-A1 INK COMPOSITION FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087576-A1 INK COMPOSITION FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 KDM4E 679/4885ALDH1A1 440/4885MAOB 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.