Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.68 |
| ▸ | TNF | P01375 | 5/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.51 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6785799 | 0.85 | ADORA2B (0.64) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL8644949 | 0.84 | ADORA2B (0.64) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL6854303 | 0.83 | ADORA2B (0.66) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL7594109 | 0.83 | ADORA2B (0.66) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL8647096 | 0.83 | ADORA2B (0.84) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL11302344 | 0.82 | ADORA2B (0.70) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL6780041 | 0.81 | ADORA2B (0.65) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL8072033 | 0.81 | ADORA2B (0.54) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL8062551 | 0.81 | ADORA2B (0.54) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL8062552 | 0.81 | ADORA2B (0.54) | ADORA2BTNFUSP2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807862-A | Therapeutic compounds containing pyrimidinyl moieties | CELL THERAPEUTICS, INC. (US) | 1998-09-15 | — | — | US | disclosed |