Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8643586 | 1.00 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL8635607 | 0.93 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL8635592 | 0.93 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL8636604 | 0.90 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL8636611 | 0.90 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL8639471 | 0.89 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL8639486 | 0.89 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL8640460 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL8640456 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL8638617 | 0.86 | KDM4E (0.67) | ALDH1A1KDM4EHPGDNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |