⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673948 | 0.80 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL11412189 | 0.75 | MEN1 (0.44) | — | |
| SCHEMBL158449 | 0.74 | — | — | |
| SCHEMBL135028 | 0.72 | — | — | |
| SCHEMBL2972 | 0.72 | — | — | |
| SCHEMBL2884608 | 0.72 | ACHE (0.42) | — | |
| SCHEMBL10822473 | 0.70 | PARP1 (0.35) | — | |
| SCHEMBL1206425 | 0.69 | — | — | |
| SCHEMBL18705898 | 0.69 | — | — | |
| SCHEMBL6555374 | 0.69 | GAA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130995-B | Pyrrolidone compound and its preparation method and application | 杭州成邦医药科技有限公司 | 2017-08-11 | — | — | CN | claimed |
| US-20150174209-A1 | INSULIN-PRAMLINTIDE COMPOSITIONS AND METHODS FOR MAKING AND USING THEM | AMYLIN PHARMACEUTICALS. LLC (US) | 2015-06-25 | — | — | US | claimed |
| EP-2091945-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2014-01-15 | — | — | EP | claimed |
| WO-2013177565-A1 | INSULIN-PRAMLINTIDE COMPOSITIONS AND METHODS FOR MAKING AND USING THEM | AMYLIN PHARMACEUTICALS, LLC (US) | 2013-11-28 | — | — | WO | claimed |
| US-RE43802-E1 | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE LLC (US) | 2012-11-13 | — | — | US | claimed |
| CN-101914080-B | Benzofuran-3-ketone substitute phenyl compound as well as preparation method and application | UNIV SHANGHAI JIAOTONG | 2012-10-03 | — | — | CN | claimed |
| US-20110301217-A1 | Selective Glycosidase Inhibitors and Uses Thereof | SIMON FRASER UNIVERSITY (CA) | 2011-12-08 | — | — | US | claimed |
| US-RE42889-E1 | α- and β- amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE LLC (US) | 2011-11-01 | — | — | US | claimed |
| EP-2344452-A1 | SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF | Simon Fraser University (CA) | 2011-07-20 | — | — | EP | claimed |
| US-20110166096-A1 | URACIL DERIVATIVES AND USE THEREOF | RESPROTECT GMBH (DE) | 2011-07-07 | — | — | US | claimed |
| US-20020052399-A1 | Alpha-and beta-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | VAZQUEZ MICHAEL L (US) | 2002-05-02 | — | — | US | claimed |
| US-5968942-A | INHIBITORS OF HIV PROTEASE | G. D. SEARLE & CO. (US) | 1999-10-19 | — | — | US | claimed |
| EP-0715618-B1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | SEARLE & CO (US) | 1998-12-16 | — | — | EP | claimed |
| EP-0715618-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | claimed |
| WO-1995006030-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | claimed |
| US-5160504-A | Colorfastness to rubbing and light, metal-tanned leather | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-03 | — | — | US | claimed |
| US-5115074-A | Condensation of carboxylic aldehyde and phenol as a novolak for heat, chemical, water resistant polymers | TEIJIN LIMITED (JP) | 1992-05-19 | — | — | US | claimed |
| US-5095100-A | Metal complex dyes and preparation thereof | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-10 | — | — | US | claimed |
| EP-0431891-A1 | Epoxy compounds, production processes thereof and cured product of the epoxy compound | TEIJIN LIMITED (JP) | 1991-06-12 | — | — | EP | claimed |
| EP-0136266-A2 | 7-Beta-acylamido-3-cephem-4-carboxylic-acid esters, process for their preparation, pharmaceutical compositions and their application | CIBA-GEIGY AG (CH) | 1985-04-03 | — | — | EP | claimed |