Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644172 | 0.96 | SCN5A (0.37) | POLBKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8642834 | 0.86 | RAB9A (0.40) | POLBKMT2AGAASMN1; SMN2PPARA | |
| SCHEMBL8645969 | 0.85 | F10 (0.40) | — | |
| Hydrochloric Acid SCHEMBL8644799 | 0.84 | F10 (0.40) | — | |
| SCHEMBL8642824 | 0.83 | GAA (0.39) | ALDH1A1GAAHDAC1HDAC2L3MBTL1 | |
| SCHEMBL8642814 | 0.83 | GAA (0.39) | ALDH1A1GAAHDAC1HDAC2L3MBTL1 | |
| SCHEMBL8650390 | 0.82 | HDAC3 (0.41) | KMT2AMEN1ALDH1A1GAASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL8646412 | 0.81 | NPC1 (0.41) | KMT2AALDH1A1GAASMN1; SMN2L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL8643480 | 0.81 | KLK1 (0.43) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL8647713 | 0.79 | POLB (0.35) | POLBKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |