Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641253 | 0.92 | NCEH1 (0.41) | NCEH1PTPN1LMNAKDM4EGLA | |
| SCHEMBL1837311 | 0.88 | NCEH1 (0.44) | NCEH1NOS2LDHALDHBPTPN1 | |
| SCHEMBL15899350 | 0.86 | PTPN1 (0.32) | NCEH1PTPN1LMNAKDM4EGLA | |
| SCHEMBL982414 | 0.86 | PTPN1 (0.37) | NCEH1NOS2PTPN1LMNAKDM4E | |
| SCHEMBL5587875 | 0.85 | LDHA (0.41) | NCEH1LDHALDHBLMNACYP1A2 | |
| SCHEMBL15899240 | 0.84 | KMT2A (0.33) | NCEH1PTPN1LMNAKDM4EGLA | |
| SCHEMBL15899244 | 0.84 | RARB (0.39) | NCEH1LMNACYSLTR2CYSLTR1 | |
| SCHEMBL15899156 | 0.84 | PTPN1 (0.34) | NCEH1PTPN1LMNAKDM4EGLA | |
| SCHEMBL15899453 | 0.82 | TSHR (0.34) | PTPN1LMNAKDM4EGLAGAA | |
| SCHEMBL1838609 | 0.80 | NCEH1 (0.48) | NCEH1LMNAKDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591923-B1 | Continuous production of aromatic carbonates | DAICEL CHEM (JP) | 1998-08-26 | — | — | EP | disclosed |
| US-5380908-A | From alkylaryl carbonates produced from dialkyl carbonates and a phenol, distillation of alcohol | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0591923-A1 | Continuous production of aromatic carbonates | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-13 | — | — | EP | disclosed |