Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | SCN1A | P35498 | 4/20 | 0.64 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.64 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637734 | 0.96 | SCN1A (0.69) | TDP1SCN1ASCN2ASCN3ATSHR | |
| Detanosal SCHEMBL2110875 | 0.90 | SCN1A (0.68) | TDP1SCN1ASCN2ASCN3ATSHR | |
| Detanosal SCHEMBL30397539 | 0.88 | SCN1A (0.66) | TDP1SCN1ASCN2ASCN3ATSHR | |
| Detanosal SCHEMBL29163805 | 0.88 | SCN1A (0.66) | TDP1SCN1ASCN2ASCN3ATSHR | |
| Detanosal SCHEMBL27797753 | 0.86 | SCN1A (0.67) | TDP1SCN1ASCN2ASCN3ATSHR | |
| SCHEMBL8641123 | 0.85 | TDP1 (0.71) | TDP1TSHRCYP3A4TP53MAPK1 | |
| SCHEMBL9765812 | 0.84 | TDP1 (0.92) | TDP1TSHRCYP3A4TP53MAPK1 | |
| SCHEMBL88285 | 0.83 | TSHR (0.81) | TDP1TSHRCYP3A4TP53MAPK1 | |
| SCHEMBL12095195 | 0.83 | TSHR (0.81) | TDP1TSHRCYP3A4TP53MAPK1 | |
| SCHEMBL29408707 | 0.83 | TDP1 (0.89) | TDP1TSHRCYP3A4TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753407-A | Polyamic acid composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5585217-A | Polyamic acid composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-12-17 | — | — | US | disclosed |