Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Butanediol SCHEMBL1696585 | 0.91 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| 1,3-Propanediol SCHEMBL14910914 | 0.91 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4450451 | 0.90 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8862241 | 0.90 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| Ethylene Glycol SCHEMBL28321709 | 0.88 | TSHR (0.64) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7916063 | 0.87 | TSHR (0.64) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9695772 | 0.86 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19017 | 0.86 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15480 | 0.86 | TSHR (0.64) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11606986 | 0.84 | TSHR (0.75) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760136-A | FORMING AN ADDITION-CONDENSATION COPOLYMER BY POLYMERIZING AN AZO-CONTAINING POLYSILOXANE AND AN UNSATURATED MONOMER; CATIONIC AND NONIONIC POLYMERS; POLYAMPHOLYTES; COATINGS; ADHESIVES; PAINTS; HAIR COSMETICS | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | claimed |
| US-4323363-A | DISPERSE DYE USED ON POLYESTERS MIXED WITH CELLULOSE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-04-06 | — | — | US | disclosed |