SCHEMBL4450451

SCHEMBL4450451

C=C(C)C(=O)OCC(C)O.C=C(C)C(=O)OCCO

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.58
THRB P10828 1/20 0.46
ALDH1A1 P00352 3/20 0.36
MAPT P10636 1/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL28321709 0.91 TSHR (0.64) TSHRTHRBALDH1A1MAPTPOLB
SCHEMBL8644707 0.90 TSHR (0.55) TSHRTHRBALDH1A1MAPTPOLB
Propylene Glycol SCHEMBL540041 0.89 TSHR (0.52) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL2461481 0.89 TSHR (0.53) TSHRTHRBALDH1A1MAPTPOLB
SCHEMBL10602461 0.89 TSHR (0.58) TSHRTHRBALDH1A1MAPTHSD17B10
SCHEMBL19017 0.89 TSHR (0.72) TSHRTHRBALDH1A1MAPTPOLB
SCHEMBL9695772 0.89 TSHR (0.72) TSHRTHRBALDH1A1MAPTPOLB
1,3-Propanediol SCHEMBL14910914 0.87 TSHR (0.60) TSHRTHRBALDH1A1MAPTPOLB
1,4-Butanediol SCHEMBL1696585 0.87 TSHR (0.60) TSHRTHRBALDH1A1MAPTPOLB
Ammonia Solution, Strong SCHEMBL28645738 0.87 TSHR (0.69) TSHRTHRBALDH1A1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133617-B2 Intumescent coating compositions SHERWIN-WILLIAMS PROTECTIVE & MARINE COATINGS (GB) 2015-09-15 US claimed
US-20150159368-A1 INTUMESCENT COATING COMPOSITIONS SHERWIN-WILLIAMS PROTECTIVE & MARINE COATINGS (GB) 2015-06-11 US claimed
EP-2530124-B1 FIBER-REINFORCED THERMOPLASTIC RESIN COMPOSITION, REINFORCING FIBER BUNDLE, AND PROCESS FOR PRODUCTION OF FIBER-REINFORCED THERMOPLASTIC RESIN COMPOSITION TORAY INDUSTRIES (JP) 2021-02-24 EP disclosed
CN-107708651-A Keratin processing 露华浓消费品 2018-02-16 CN disclosed
EP-2530124-A1 FIBER-REINFORCED THERMOPLASTIC RESIN COMPOSITION, REINFORCING FIBER BUNDLE, AND PROCESS FOR PRODUCTION OF FIBER-REINFORCED THERMOPLASTIC RESIN COMPOSITION Toray Industries, Inc. (JP) 2012-12-05 EP disclosed
EP-2121063-A2 METHOD OF FORMATION OF VISCOUS, SHAPE CONFORMING GELS AND THEIR USES AS MEDICAL PROSTHESIS Uluru Inc. (US) 2009-11-25 EP disclosed
US-20080228268-A1 Method of Formation of Viscous, Shape Conforming Gels and Their Uses as Medical Prosthesis ULURU, INC. 2008-09-18 US disclosed
WO-2008112705-A2 METHOD OF FORMATION OF VISCOUS, SHAPE CONFORMING GELS AND THEIR USES AS MEDICAL PROSTHESIS ULURU, INC. (US) 2008-09-18 WO disclosed
US-7361407-B2 Stain resistant coating compositions, methods of coating and coated articles BASF COATINGS JAPAN LTD. (JP) 2008-04-22 US disclosed
US-20040202873-A1 Stain resistant coating compositions, methods of coating and coated articles BASF NOF COATINGS CO., LTD. 2004-10-14 US disclosed
EP-0566353-B1 Photopolymerizable composition MITSUBISHI RAYON CO (JP) 1998-08-19 EP disclosed
EP-0337442-B1 Photosensitive resin plate for flexography NIPPON PAINT CO LTD (JP) 1995-08-02 EP disclosed
US-5322762-A High contrast, visible after irradiation; tribromomethyl phenyl sulfone, leuco diamond green, and dye MITSUBISHI RAYON CO., LTD. (JP) 1994-06-21 US disclosed
EP-0566353-A1 Photopolymerizable composition MITSUBISHI RAYON COMPANY LTD. (JP) 1993-10-20 EP disclosed
EP-0300505-B1 IMAGE-RECEIVING SHEET FOR THERMAL TRANSFER PRINTING KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-10-13 EP disclosed
EP-0337442-A2 Photosensitive resin plate for flexography NIPPON PAINT CO., LTD. (JP) 1989-10-18 EP disclosed
EP-0300505-A2 Image-receiving sheet for thermal transfer printing KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-01-25 EP disclosed