Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735770 | 0.86 | KMT2A (0.55) | CTSSKMT2A | |
| Proline SCHEMBL8645011 | 0.85 | PSENEN (0.47) | CTSSCTSKKMT2APOLBCTSL | |
| SCHEMBL8648699 | 0.85 | KMT2A (0.51) | CTSSCTSKKMT2ACTSLCA2 | |
| Glycine SCHEMBL27714931 | 0.83 | KMT2A (0.51) | KMT2A | |
| SCHEMBL5011681 | 0.81 | CTSS (0.50) | CTSSCTSKKMT2AALDH1A1CTSL | |
| SCHEMBL27485069 | 0.81 | CTSS (0.50) | CTSSCTSKKMT2AALDH1A1CTSL | |
| SCHEMBL16710011 | 0.79 | CTSS (0.67) | CTSSCTSKKMT2APOLBL3MBTL1 | |
| SCHEMBL2159319 | 0.79 | CTSS (0.67) | CTSSCTSKKMT2APOLBL3MBTL1 | |
| SCHEMBL629960 | 0.79 | CTSS (0.67) | CTSSCTSKKMT2APOLBL3MBTL1 | |
| SCHEMBL3825684 | 0.79 | CTSS (0.67) | CTSSCTSKKMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610743-B1 | Aminomethylene-peptides as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5385918-A | Aminomethylene-peptides as immunosuppressants | MILES INC. (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0610743-A1 | Novel aminomethylene-peptides as immunosuppressants | Bayer Corporation (US) | 1994-08-17 | — | — | EP | disclosed |