Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227199 | 0.72 | MEN1 (0.52) | KMT2AMEN1MAPTGAARAB9A | |
| SCHEMBL11230099 | 0.67 | MEN1 (0.47) | KMT2AMEN1MAPTGAARAB9A | |
| SCHEMBL14709206 | 0.67 | MEN1 (1.00) | KMT2AMEN1MAPTGAARAB9A | |
| SCHEMBL13876845 | 0.66 | TNKS2 (0.66) | KMT2AMEN1MAPTGAARAB9A | |
| SCHEMBL4090554 | 0.66 | TNKS2 (0.66) | KMT2AMEN1MAPTGAARAB9A | |
| SCHEMBL2046465 | 0.61 | HTR2A (0.47) | KMT2AMEN1MAPTGAARAB9A | |
| SCHEMBL7608325 | 0.61 | MEN1 (0.42) | KMT2AMEN1MAPTGAARAB9A | |
| SCHEMBL9634391 | 0.61 | KMT2A (0.49) | KMT2AMEN1MAPTGAARAB9A | |
| Catechol SCHEMBL28545800 | 0.61 | ALDH1A1 (0.67) | KMT2AMEN1MAPTGAARAB9A | |
| SCHEMBL31169126 | 0.60 | ALDH1A1 (0.47) | KMT2AMEN1MAPTGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712408-A | Diaminomaleonitrile derivative compounds, polymers, and method of producing same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-01-27 | — | — | US | disclosed |